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Select the correct option:
This is _________________________ pen.
The sentence is indicating possession of an object, the correct answer is my, as it's the possessive form of the pronoun "I" indicating that the pen belongs to the speaker. Mine is also a possessive form of "I" it's only used when the noun is not mentioned. I is the pronoun that refers to the speaker and me is the pronoun that is used as the object of the verb or preposition.